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Cellares Inks Long-Term Lease for IDMO Smart Factory at Leiden Bio Science Park
45+ min ago (180+ words) Co-founders Omar Kurdi (left) and Fabian Gerlinghaus (right) with The Cellares Cell Shuttle [Cellares] The leased premises comprise approximately 9,741 square meters (about 105,000 square feet) of laboratory and office space within the Nexus building in Leiden, a newly constructed life sciences…...
GI Tract Protein Defensively and Offensively Protects Against Microbial Threats
1+ hour, 46+ min ago (879+ words) Studies showed that a human lectin has broad-spectrum antimicrobial activity against bacteria found in the gastrointestinal tract. The results showed intelectin-2 has a dual function, strengthening the mucus barrier, and also neutralizing or eliminating pathogens. The post GI Tract Protein…...
Improving Biopharma Sponsor Access to Clinical Trial Imaging Data
14+ hour, 39+ min ago (526+ words) Improving Biopharma Sponsor Access to Clinical Trial Imaging Data'Genetic Engineering and Biotechnology News Credit: imagestock / iStock / Getty Images Plus Yvete Toivola, PhD, is the vice president of Product Development at Flywheel, where she leads the development of imaging-centered data platforms…...
Simple Workflows for Complex Genomics: Expanding Clinically Relevant Findings with Enhanced Exomes
14+ hour, 55+ min ago (259+ words) In this GEN webinar, Guilherme Yamamoto, MD, PhD, and Sevana Yaghoubian will present a novel whole-exome assay for detecting high-confidence variants across multiple applications. The post Simple Workflows for Complex Genomics: Expanding Clinically Relevant Findings with Enhanced Exomes appeared first…...
Cryo-EM Maps Autoantibody Hotspots on NMDA Receptors in Autoimmune Encephalitis
15+ hour, 49+ min ago (549+ words) Using near-atomic cryo-EM, scientists mapped where pathogenic autoantibodies bind to NMDA receptors in the brain, identifying hotspots that could improve diagnosis and therapies for "Brain on Fire" disorder. The post Cryo-EM Maps Autoantibody Hotspots on NMDA Receptors in Autoimmune Encephalitis…...
Framework to Optimize Mammalian Cell Culture Media Blending
20+ hour, 45+ min ago (122+ words) Credit: Westend61 / Getty Images In a recent paper, Hirotaka Kuroda and Kazuya Sorado, of Osaka University and Shimadzu, and Noriko Yamano-Adachi and Takeshi Omasa, of Osaka University and the Manufacturing Technology Association of Biologics, address this gap with a mathematically precise…...
Biologics Manufacturers Urged to Develop QC Plans Early
20+ hour, 46+ min ago (302+ words) By Vivienne Raper, PhD At a conference early next year, biologics manufacturers will be encouraged to develop a chemistry, manufacturing, and controls (CMC) management strategy for their reference material early in development to avoid later potential risks. "Agencies want you to…...
Regulatory Support Helping Biopharma to Embrace Platform Technologies
20+ hour, 46+ min ago (427+ words) By Gareth John Macdonald Credit: Gorodenkoff / iStock / Getty Images Plus Platform technologies'base systems used to make multiple products'are gaining in popularity in biopharma with more and more firms adopting modular manufacturing strategies to bring down costs. So says Vishnu Kumar,…...
Digital SHERLOCK: Rapid Detection and Resistance Profiling of Candida auris
21+ hour, 3+ min ago (623+ words) dSHERLOCK, a rapid CRISPR-based diagnostic that detects Candida auris from patient swabs and identifies antifungal resistance mutations, could enable faster treatment decisions and improved control of hospital outbreaks. The post Digital SHERLOCK: Rapid Detection and Resistance Profiling of Candida auris…...
Drugs from the Deep
1+ day, 1+ hour ago (358+ words) By Mike May, PhD From cancer treatments to antiviral therapies, some of today's most powerful medicines trace their origins to an unexpected place: the ocean. But while the sea holds enormous pharmaceutical promise, scientists say the challenge has always been…...